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CBD Doesn't Work for Everyone - Here's Why

 

Why CBD Oil Doesn’t Work For Some People - Read on...

 

The results are in, CBD is providing miraculous relief from common problems like anxiety, insomnia, fibromyalgia, hypertension to chronic pain from past injury and arthritic conditions.

 

Absolutely no substance is 100% effective for everyone; nothing is. While CBD works wonderfully for the majority of people, it simply does not work on everyone the same way and in some cases not at all for others. The reasons may be surprising while some of them should be obvious. That is why it can be disappointing to hear people report that CBD is a scam because it did not work for them. Most people fail to realize is that there are many potential reasons why CBD oil didn’t work for them and it has absolutely nothing to do with the efficacy of CBD as a whole. So, let’s go into some of the reasons CBD products may not work.

The Brand And type of CBD Products, Isolates VS Full or ‘Broad Spectrum’ CBD greatly affect bio-availability and efficacy. 

Let’s face it, in an unregulated and relatively new industry inevitably there will emerge bad actors that sell inferior products and make outrageous claims to make a fast buck. The good news is that eventually they will end up out of business. The bad news is they will do irreparable harm to the industry and prevent a lot of people that would have otherwise benefited from this wonderful natural gift from ever trying it. So who are these people and what are they selling? Let’s start with what is actually in the products being sold. The majority of CBD products available for sale online, in smoke shops, whole foods and corner stores are primarily cheap CBD isolate mixed with glycerin or some form of MCT oil (medium chain triglyceride). The reason for this is isolates are cheaper to produce and only contain CBD (cannabidiol) from the plant. While isolates can and do work on some levels, they lack the essential terpenes and balance of the cannabidiol profile provided from a Full spectrum product.

Type of CBD product CBD isolate is exactly that, ISOLATED CBD. When manufactured all the plant matter and bi-products including essential oils, waxes, chlorophyll, and more are removed, leaving only CBD and nothing more. Sadly, the essential oils, terpenes and other cannabidiols that are removed actually work synergistically to provide a broader range of efficacy. So why do they manufacture isolates? Because it is quick and cheap. Modern manufacturing processes make it simple to isolate any given compound while it is complex and costly to separate and preserve individual components of the entire plant profile.

Full Spectrum / Broad Spectrum: Full Spectrum CBD contains hundreds of different phytochemicals including cannabinoids, terpenes, and a host of other compounds that are known to have an effect on the endocannabinoid system of the human body. Full or ‘Broad Spectrum CBD products’ are produced utilizing the whole plant and all of its parts from stems stalks and flowers to seeds. While Full spectrum contains the CBD (cannabidiol) found in isolate formulas it also contains a broad or full spectrum of the plant’s molecules such as essential vitamins, minerals, fatty acids, proteins as well as chlorophyll, terpenes and flavonoids. Unlike a CBD product that is isolated and reconstituted in MCT oil, Full spectrum provides all of the plant’s molecular compounds allowing the plants medicinal benefits to work together the way nature intended them to. This is also referred to as a full entourage effect, which cannot be obtained using only a CBD isolate.

So, what does this mean for you? Well quite simply if you purchased a CBD isolate you are only getting one part of the plant and not the entire plants profile, which can have a profound effect on the way it works. To add insult to injury there are a lot of very popular products sold by unscrupulous companies claiming to produce a full spectrum CBD product when in fact they are selling an isolate. This does the entire industry a dis-service and discourages people from using something that could potentially change their lives.

Potency and Purity: Many companies intentionally mis-label their bottles claiming to contain upto1,000mg of CBD when in reality they have 200mg or less. As a consumer there is literally no way of knowing the actual amount of CBD in the product you have purchased. Some companies will even go as far as fabricating or altering the certificates of analysis which is about as bad as it gets.

Dosage, Dosage, Dosage: If you are fortunate enough to be using a quality brand, are you actually taking enough? Are you taking to little? Are you taking the correct amount and strength for your height and weight? And are you using it once, twice or three times day? Generic dosage recommendations vary from each manufacturer and there is no end to how much or when to take your ideal CBD dose. Keep in mind we are all genetically diverse and tolerate pain and substances differently. So ,what may be ideal for you may not work at all for the next person. It really is an exercise in self-discovery that will determine how much or how little you should take.

Here are some examples: Each bottle contains 30 ml (1oz) of Tincture (CBD Oil) at 1/4 dropper 0.25ml = 10 drops. Each bottle should yield from 30 to 120 servings depending on individual dosage. Each Dropper is capable of up-to a 1.0 ml dosage (approximately 3/4 full) most people dose at or under 0.25ml or 1/4 dropper full. A single 0.25 ml dose from a 500mg bottle = approximately 5.0mg per dose. So, at 1/4 dropper per serving from a 500 mg bottle your actually consuming 5mg of CBD per dose.

So what exactly is the right dose? That depends on the individual and what they are trying to treat with CBD. Dosage varies depending on the mg per bottle of CBD oil you are using. On an average, 2mg to 5mg of CBD a day has shown to improve sleep and reduce anxiety. 10mg to 15mg has been shown to decrease symptoms resulting from autoimmune or chronic pain issues like arthritis and fibromyalgia. In order for CBD to be effective for most people the dosage of CBD should be minimal and increased slowly until the symptoms improve. This, of course, is different for every person and should be monitored closely. Building up levels of CBD is important for it to work properly so don’t expect instant gratification. As your body begins to experience the effects of CBD, new and healthy neurological pathways should start to form sustainable symptomatic relief can be achieved but you have to be patient. Always begin with a low dose and gradually increase until you feel an effect then decrease based on need. If you end up going as high as 100mg a day for pain relief and it isn’t working, then re-visit the potential reasons previously listed.

CBD Is A Biphasic Substance: That means that specific amounts of CBD provide varied effects on the human body. Biphasic effect may be a new term to most people, but, is a very common occurrence. Meet Anne, Anne can inhale once from a marijuana joint and get very high, while her friend Michelle can finish smoking the entire joint and feel fine. Meet Paul, Paul can have a few drinks and become socially engaged but if Paul consumes several more, he’s in the bathroom passing out in the stall. This is what is referred to as the biphasic effect. That does not mean CBD will act as a stimulant at one dosage amount and a depressant at another, but the effect can and do change as your dosage increases or decreases. If your new to CBD it’s vital to record your experience so you can fine-tune your intake and discover works for you.

Genetics: Unfortunately, your personal genetic makeup may be to blame. If you have genetic anxiety issues for example, you could experience bouts of paranoia when using THC in medical or recreational marijuana on the contrary THC FREE CBD should help reduce the effects of anxiety and stress. CBD works directly with the human endocannabinoid system ECS) and believe it or not, some of us are born with more endocannabinoids than others. For the record, around 20% of Americans have a genetic mutation that increases the natural endocannabinoid level in the body. If you’re lucky enough to have this mutation, you’ll feel less anxious than a normal person but conversely, since you have extra cannabinoids already, CBD may prove ineffective. Incidentally, you can use a service such as 23andMe to predict how you’ll respond to weed.

Biological Factors: Females are naturally more sensitive to cannabinoids and those that suffer from pain or anxiety are more likely to benefit from CBD. A woman’s menstrual cycle also has an impact on how cannabinoids work. THC is believed to work closely with estrogen, so CBD in women with elevated estrogen levels appear to benefit most. Men are typically larger than women, produce more testosterone than estrogen and usually require higher doses of CBD than a woman to achieve the same results.

Biochemistry, Individuality & Lifestyle Considering individual genetic diversity and biological differences in the sexes, as a species we are all the same yet vastly different. Simply put some of us are more sensitive to CBD and cannabidiol than others. Factors such as stress, diet, physical fitness and lifestyle choice have a huge impact how the Endocannabinoid System functions. If CBD has not worked for you in the past, take a closer look at your lifestyle, and dietary intake. If your diet is low in fatty acids like omega-3, your endocannabinoid system will not function at an optimal level. Our hemp rich CBD oil is a form of fatty acid and contains high levels of omega 3 as well as Gama-linolenic acid, behenic acid and lignoceric acid. If your CB2 and CB1 receptors are out of balance CBD will not be as effective on you because your biochemistry directly affects your endocannabinoid balance.

Physical Health If you’re in excellent shape with no real ailments, CBD oil won’t help as much as if you had a chronic condition such as fibromyalgia. Individuals with chronic medical conditions tend to have altered body chemistry and when you take CBD, it will produce a number of chemical interactions in the body which work to restore internal neural homeostasis. CBD is a pleiotropic substance what this means is that cannabidiol produces simultaneous compounded effects through multiple molecular pathways in the human body. Pleiotropic effect produces multiple benefits from the same substance meaning, it has an effect on more than one symptom or problem at the same time. For example, someone may use it for anxiety and it simultaneously reduces their blood pressure while reducing inflammation, creating a pleiotropic effect.

Psychological Health CBD is more effective if you suffer from Psychological Disorders like anxiety, depression, PTSD or any other issue that affects mental health. Chemical imbalances in the brain are partially to blame for mental disorders. If you are currently taking medication to control any of these disorders it is strongly recommended you consult a physician prior to Introducing CBD. While CBD may help restore chemical balance, significant dosages of CBD will temporarily deactivate cytochrome P450 enzymes, thereby altering how we metabolize a wide range of compounds and potentially interfere with your medications.

The Entourage Effect means that CBD oil is more effective when it contains all of the plant’s beneficial compounds or the full-spectrum of the plants chemical profile. The chemical compounds naturally found in cannabis like the plants terpenes and flavonoids have additional medicinal benefits. There have been studies that now suggest CBD is not as effective when taken in isolate form. The most effective CBD products combine a broad profile of cannabinoids. Doc Green Well produces a complete line of Full spectrum high potency and extremely pure CBD oils, CBD Edibles and CBD Topical’s. Learn more about Doc Green Well products here

A Final Thought on CBD Products. If you end up being in the minority of people that CBD oil did not work for you, please don’t automatically dismiss the effectiveness of this wonderful all-natural remedy. CBD is a great alternative to addictive and toxic pharmaceutical drugs. If you have tried CBD in the past and felt no immediate or dramatic effect, do not assume that CBD products don’t work. Re-visit the list of reasons outlined in this article and see if any of the above-mentioned circumstances apply to you. Remember an inferior CBD oil, personal genetics or biochemistry may the underlying reason it did not work to your expectations. Don’t forget it may as simple as taking too low of a dose or not taking it long enough.

 

From the original: https://www.docgreenwell.com/why-cbd-does-not-work/
Posted in CBD on February 05 at 03:08 PM

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